[PRE-IMPLANTATION GENETIC TESTING]
New technologies to increase the efficiency of IVF
PGT - WHAT IS THAT?
Preimplantation genetic testing (PGT) is a method for identifying embryos with gene and/or chromosome abnormalities.
One of the reasons for failed IVF attempts is the transfer of an embryo withchromosomal abnormalities.
To prevent this, preimplantation genetic testing (PGT) is performed to identify embryos with gene and chromosome abnormalities.
Only healthy embryos are transferred into the uterine cavity, which greatly increases the efficiency of IVF.
PGT HAS A POSSIBLE
Prevent the birth of a child with chromosomal diseases.
Reduce reproductive losses during pregnancy.
Increase the effectiveness of IVF.
Mother's age >35 years.
Habitual pregnancy failure.
Multiple failed IVF attempts.
Some forms of male infertility associated with chromosomal abnormalities.
Carrying chromosomal rearrangements, translocations, inversions, and other chromosomal abnormalities.
FREQUENCY OF CHROMOSOMAL ABNORMALITIES IN FEMALE EMBRYOS
According to statistics, after one IVF protocol, children are born in 41% of cases.
The percentage increases to 69% when PGT is performed.
HOW DOES THE PROCESS WORK?
The couple goes to the clinic and undergoes IVF preparation and egg and sperm biopsies
The egg is fertilized with a sperm cell
on day 5 of embryonic development, a biopsy is taken and 3-5 cells are taken for examination
The sample is sent to the TreeGene laboratory in Almaty
the embryo is frozen by cryopreservation
NGS genetic study is performed within 2-4 days
the finished result is sent to your doctor
If the embryo passes the selection criteria, it is transferred into the uterine cavity
the process ends with a long-awaited pregnancy
BENEFITS OF THE NGS METHOD
High resolution by nucleic acid sequencing.
Potential for simultaneous diagnosis of chromosomal and monogenic pathology.
A more sensitive method than aCGH, it can detect 20% mosaicism, numerical and structural abnormalities of chromosomes.
Quantitative analysis of mitochondrial DNA.
Fast technology with results the next day.
RESULT is issued according to the guidelines for prioritizing embryos for transfer, based on the PGDIS regulation (08/19/2016)
1 embryo - 141 500 tenge
HOW AND WHERE DO I PASS?
The study is conducted in our laboratory TreeGene in Almaty, at the address: Anosova 98, 2nd floor.
We can give you advice and answer your questions. But the collection of cells for the study is taken directly in the Reproductive Center. If you want to do Preimplantation Genetic Testing by NGS, you need to contact your fertility doctor.