Lactose in the human body is broken down into two components. This occurs under the action of the lactase enzyme, the synthesis of which is encoded by the LCT gene .
Lactase is the only enzyme in mammals that can break down lactose. Lactose intolerance in adulthood is caused by a gradual decrease in the activity of the lactase enzyme.
However, in some people, lactase activity persists throughout life. This enzyme activity is determined by changes in the LCT gene.
The genetic test will allow you to find out your gene variant. There can be a total of three: C/C, C/T, and T/T.
C/C is the norm for the LCT gene.
WHAT IS LACTOSE?
Lactose is the main carbohydrate in mammalian milk. Lactose accounts for 85% of all carbohydrates in milk. Forty percent of a baby's energy needs during breastfeeding are met by the presence of lactose in milk. It is 80 to 85 percent of all carbohydrates in milk.
WHY DON'T YOU HAVE TO GIVE UP DAIRY PRODUCTS COMPLETELY?
1. When lactose is broken down, lactic acid is released, which inhibits the growth of pathogenic bacteria, putrefactive and gas-forming flora
Lactose stimulates the growth of normal intestinal microflora as a prebiotic
3.Lactose acidifies the intestinal pH
Lactose is involved in the synthesis of galactose, a carbohydrate that the baby needs in the first months of life
5.Lactose helps the absorption of calcium, magnesium, potassium, manganese, zinc
Lactose is involved in the synthesis of B vitamins
WHO WILL BENEFIT FROM THIS TEST
from 1.5-2 years of age, since before one year of age lactase is produced in the body regardless of the gene variant
Nutritionists, gastroenterologists, pediatricians, nutritionists
Who has symptoms and is interested to know the peculiarities of their body
HOW IT MANIFESTS ITSELF
Lactose intolerance is a consequence of lactase deficiency, which can be due to genetic predisposition or environmental factors. It occurs after a period of breastfeeding.
In either case, the symptoms are caused by insufficient levels of lactase in the duodenal mucosa.
Lactose cannot be directly absorbed through the wall of the small intestine into the blood, and in the absence of lactase, the sugar molecules pass without enzymatic cleavage into the large intestine.
Bacteria in the colon can metabolize lactose and release a mixture of gases (hydrogen, carbon dioxide, and methane), resulting in various intestinal disorders.
Unabsorbed sugar and fermentation products also increase the osmotic pressure, which leads to an influx of water into the intestinal cavity and, consequently, to diarrhea.
HOW COMMON IT IS
[ Lactose intolerance (C/C gene variant) is found in 60% of the population in KAZAKHSTAN ]
In all healthy newborns lactase is produced in large quantities, but by the end of the first year of life the activity of the enzyme decreases 2-4 times. The age dynamics of this process are also variable.
The almost complete absence of lactase activity in adulthood can begin at 2 years of age (in the Chinese) and up to 20 years of age in the peoples of northwestern Europe.
HOW TO TAKE THE TEST?
Your version of the gene
Useful and interesting information about lactose