JAK2 Mutation Val 617phe

The JAK2 gene ANALYSIS is needed:

for diagnosis of myeloproliferative diseases.
to exclude secondary causes of elevated platelet levels (secondary thrombocythemia) and erythrocytes (secondary erythrocytosis).

Myeloproliferative diseases (MPD) are diseases characterized by overproduction of one or more hematopoietic cells. Disorders occur at the stem cell level, which can lead to erythraemia, subleukemic myelosis, thrombocythemia, and chronic myeloleukemia.